This is like the memes calling Trump and Putin gay, you aren’t hurting your target, you are just further marginalizing normal people who struggle with these issues.
Can’t say for certain without knowing exactly which memes you’re talking about but the ones I’ve seen are often the opposite. The butt of the joke is their ‘hypermasculinity’, drawing attention to how ridiculous the concept is and thereby trying to destigmatize being gay or at least being more open to ‘gay’ behaviours (e.g. empathy).
There’s also ones where they’re directly accused of being closeted (e.g. Graham) which is a bit more harmful but even then it seems strategically positive in that allies won’t care, and if it gets the hateful ones to turn on them that improves conditions for the vast majority of ordinary lgbtq+ members.
Over what time period are we talking though?
Like the Wikipedia article says 10-100M and up to 95% died from plagues brought over from ~1500-1618, but I can’t tell if the sources are any good/reliable.
Does this count or does it mean that of those who remained, a further 75% got genocided? Or is it referring to some specific even later genocide.